I like the open back aka fish room. what I'm going to highly recommend HIGHLY recommend is having front access. it may not be bad on the 12o but its a PAIN to get into my tank from the back. i only really access it from the front. If i were you i would put front access panels on your in wall. i talked to a couple people that didn't have it and they said if they could do it over they would have front access. I really liked the picture frame but not that i have the front access i am so happy i tried accessing it from the back and its hard you have to have 2 people or be able to use a picker stick while trying to see your reflection off the front glass its super hard lol
It's planned on a wall where the front will be facing the living room and the back will be in the aquarium room- quarantine tank and live rock tanks. So accesses from both sides will be possible. I'm going to flush it on the front side with the wall and build the walls out on the back.
Think I have a lot more planning to do, but I will definitely plan front accesses in. Thanks!