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I gotten really good at targeting them with a kalkwasser slurry by using one of those small, 3ml liquid medicine doses I get from my vet when the cats are sick. Best when lights are off or low and my softies are still deflated. If I can’t get them with the kalkwasser then I use the 2 part epoxy and cover them up. Works good when they are on an edge of the rock.
Of all the things I've tried - ORA aiptasia eating filefish. It takes up to two weeks (in my experience) to see aiptasia vanish. One note - filefish eat them at night - so one day you'll have aiptasia everywhere next day aiptasia gone, filefish fat and happy.
Not to be a stickler, but this is not a solution.
Most may not want another fish. Some cannot keep another fish. You may have to possibly supplement food to the filefish or give it away after. Filefish do not fit into pipes, overflows and sumps. You may as well just baste them with hot RODI water, it won't take 2 weeks.
Superglue is your best chance to kill a polyp and not have it spread. IME. This assumes you can access the rock. If you have a big tank you will have to try and use the glue underwater I guess. I've been taking the rock right out of the water to apply the glue.