Sorry bro - I'm going to disagree with you on this as well - again slightly - difficulty is in the eye of the beholder - but - each time you 'clean' a canister filter (and with a saltwater tank - unless doing large water changes (which is also fine) - the o-ring seems to get closer and closer to leaking and causing potentially huge damage. I have used most of them in freshwater - and just won't do it again.Sand and live rocks require a sump and no where as efficient as a canister for equivalent space or fact I can take out that canister, if needed. I can run multiple canisters where one sump would take up space as well as eliminate overflows and worry of flooding or the noise associated with sumps. It's not for everyone but some of us rather not deal with the headaches and why my main being designed as an AIO with a closed loop system and various canisters along with Big Blue whole house filters. Going to be quieter, less chance of flooding, minimal maintenance and still allows me to hide equipment such as heaters, dose as needed and refugium in the final compartment before return to tank. It's all in the design but for someone wanting simplicity and lacking the space for a sump then canisters can solve their issues.
BTW, cleaning a canister isn't complicated. Key is shutting flow in and letting some of the water to exit before closing off effluent than shutting pump off as you know already. Makes moving the canister easier with less water weight and no spillis when opened because water internally lower. Those FX makes this even easier with the ability to fully drain, if needed. Although I grasp that can be a hassle bi-weekly tying to service floss and GAC and why adding a second smaller unit solves that problem. HOB an even better option.
You can certainly do it - to me the major advantage (and practically the whole advantage) - is 1. Hiding the stuff under the tank (protein skimmer, etc) - and 2. markedly increasing the total water volume of the system. For example a 20 gallon tank with a 20 gallon sump effectively from the waste standpoint makes it 40 gallons etc etc.