Add the med now, then change water and add med again this evening.
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I know this thread is pretty old, but I just read most of it bc I have a mag coming next week and I want to be ready for it. OrionN and the others that contributed to ironing out this process and making it a successful one, thank you.
I do have to comment that the ones that are SO worried about the Antibiotics entering the environment I actually find that funny. First off, at 250 mg per 10 gallons over the course of a week /treatment cycle you are looking at a total of less than 2 grams entering the sewers prior to treatment. This doesn't even take into consideration any type of degradation that's caused from extrinsic variables such as light and the water plant/treatment center . How many salt water hobbiest out there? Quite a few right? How many of those hobiest have reef tanks? Still A good amount but less. How many of those keep anemones? Less than previois but prob a good number. How many of those keep Mags? A LOT less than the total number of aquarist that keep reef tanks. Of those that keep Mags, how many are utalizing a procedure that involves the dumping of Cipro... A LOT less.
With that said... how many chicken/poultry, beef, and pork farms are in the US? - Over 1.3 million that sell livestock for consumption. Now imagine all the wash off or elimination enterinf the environment from all the antibiotics that are constantly being put into the livestockS food. We're talking hundreds of pounds a day across the board.. now that's something to worry about. Not the salt water hobbiest in a clandestine lab trying to save an anenome...