in this topic I will be referred to Vanessa and They is referred to Chemiclean throughout this statement. OK by the sheets i got faxed today there are no problems with the breaking of the compounds, the can be a increase enzymes. I was told that a good way to start the product for the purpose of medicating a salt water environment is mixing it in hot water, this insures a total breakdown. there is a possibility that the medication has not broken down properly creating a mass, if that said mass collides with a secretion or the chemical imbalance. In turn may cause a.... and i feel in my opinion that the drug in this manner may break down the oxygen. at this point they are stating that they inform customer full knowledge that their oxygen needs to be at at least an 9% higher then normal rate for the first 12 hours. There should not be any harm if there is nothing decaying or raising amona levels. there will always be different situations on how the medication that is called Chemiclean will react to many different situations, this drug was tested and reviewed for 2 years before getting FDA approved. I believe that they would stand by there product if notified that you had a full crash they would help you to determine the cause best to there abilities without knowing how said person took care of there salt water aquarium. If this product used over 12 hours will increase enzymes at a .0023 rate per amount used in that time. If a perimeters are in a safe and producing manner you could mix said product in hot water and dump it all in and be safe. One note that I offer is that I have learned that people like to raise their salt water adventure to there liking, you may or may not like the product but they are valid in all FDA rules and regulations. I myself will not be using this product because I feel that I would like to use another avenue. SO it comes down to..... do you think that your tank can with increasing the oxygen withstand the said product compounds and chemicals. Chemicals may collide in any situation, it is a personal choice that has to be made when you are using toxic chemicals. Thank you for letting me look into this if you have any medication questions regarding breakdowns through FDA just give me a shout